Leadership

Our leadership team has deep experience and a track record of success to guide our people and our work.

Ian F. Smith

Chief Executive Officer & Director

Jonathan Allan, J.D.

General Counsel

Ryan Arnold, D.O.

Senior Vice President and Head, Global Medical Affairs

Isabel Aznarez, Ph.D.

Senior Vice President, Head of Research
and Co-Founder
Photo of smiling businesswoman in hallway

Sara Den Besten

Chief People Officer

Jason Hoitt

Chief Patient Officer

Dawn Kalmar

Chief of Corporate Affairs and Strategic Partnerships

Katherine Lefeber

Vice President, Corporate Strategy and Chief of Staff

Tommy Leggett

Chief Financial Officer

Beth Mellen, MS, MBA

Chief Regulatory Officer

Barry Ticho, M.D., Ph.D., FACC

Chief Medical Officer

Board of Directors

Arthur Tzianabos, Ph.D.

Chairman

Ian F. Smith

Chief Executive Officer & Director

Adrian Krainer, Ph.D.

Co-founder & Director

Jennifer Burstein, MBA, CPA

Director

Seth L. Harrison, M.D.

Director

Edward M. Kaye, M.D.

Director

Arthur Levin, Ph.D.

Director

Garry E. Menzel, Ph.D., MBA

Director

Julie Anne Smith

Director

Stoked By Science

Our story began in the lab with our founders, who shared a passion to address genetic diseases.

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